Wade Regehr’s doctorate was at the interface between neuroscience and electrical engingeering. Regehr’s laboratory studies the implication of calcium Ca2+ as it affects synaptic strength. Neurons communicate with one another via synapses. Regehr was one of the first to use fluorescent imaging to see the synaptic activity occurring in the brain. By studying the physiological process and mechanisms, a further understanding is made of synaptic depression and delayed release of the neurotransmitter, synaptic potentiation, facilitation and other calcium dependent chemical processes.[1] Regehr’s study of short term synaptic plasticity (synapse strength during behavioral tasks) is relevant toneurological disorders such as epilepsy, schizophrenia and depression